The entire human race history is insignificant in the face of their planet's lifespan.
The planet's lifespan is insignificant in the face of its galaxy's lifespan.
The galaxy's lifespan is insignificant in the face of the universe's existence.
And for certain there's something out of universe that's even greater.
So how great can a setback be for an individual's disappointing moment, in a brief moment of days, months or years?
Life is just a matter of years in about a century. So face all setbacks bravely, and move on to do the best you can till the end.
